Alzheimer’s & Cognitive Rehabilitation Program

Changing from Symptom-Based Support to Proactive Restoration at the Level of the Brain Cells

PYONG Rehabilitation provides 2 forms of choice in caring for Alzheimer's patients: the programme of brain stimulation with the technology Transcranial Pulse Stimulation | TPS, and the intensive programme of restoration of the ability of the brain

Both programmes can be integrated together according to the symptoms of the patient and the goals of the treatment

Tell us the symptoms or the concerns, and receive recommendations for the assessment and the treatment in the first stage

This programme is suitable for

• Alzheimer's patients from the early to the moderate stage (Mild to Moderate)
• Those who have a state of slight deficiency of cognition (Mild Cognitive Impairment)
• Those who have a state of dementia from cerebrovascular disease (Vascular Dementia)
• Parkinson's patients who have a problem of balance and of walking (Gait & Balance issues)
• Older people who have a state of forgetfulness with age and want prevention before entering the stage of dementia

A New Breakthrough in Alzheimer’s Treatment

Transcanial Pulse Stimulation | TPS

A New Choice for Restoring the State of the Brain and the Symptoms of Alzheimer's Disease

TPS — Transcranial Pulse Stimulation — is an advanced innovation of brain stimulation from Switzerland, which has received certification at the international level in respect of treating the symptoms of Alzheimer's disease, and has evidence that can be seen from research, that it can help restore the symptoms of Alzheimer's disease and slow the degeneration of the brain

TPS works by sending sound waves of a high frequency that have a high specificity (Focused Acoustic Pulses) into the brain tissue as deep as 8 centimetres, in order to stimulate the creation of a new network of nerves and increase the secretion of the biomolecular substances necessary for the continuing existence of the brain cells, without giving rise to heat that is dangerous to the cells

The results from the clinical trials:

• Restoring the working of the brain: helps the front part of the brain process more quickly, increases the ability in remembering (Memory) and in deciding (Executive Function)
• Reducing the state of depression and anxiety: helps reduce the psychiatric state and the symptoms of anxiety arising from the state of the brain
• Stimulating the brain precisely and safely: not invasive, no accumulated heat that is dangerous to the cells
• Maintaining the result in the long term: with treatment of 30 minutes, 6 times, in 2 weeks, and treatment to maintain the result every 4-6 weeks

Those receiving the service can choose to restore the state of the brain with the programme Transcranial Pulse Stimulation | TPS on its own, or combined with the intensive programme of restoration of the ability of the brain, according to the symptoms of the patient and the goals of the treatment

In this, the programme of treatment that is suitable specifically to the individual will receive an assessment by the physician again after the diagnosis

Stimulating the Brain with Sound Waves of a Specific Frequency, Without Surgery

Sending sound waves of a specific frequency (Focused Acoustic Pulses) into the brain tissue, in order to stimulate the connection of the network of the nerve cells, and to promote the biological mechanisms connected with the continuing existence and the working of the brain cells

Delivering Energy into the Brain Tissue Precisely as Deep as 8 Centimetres

It has high precision and can deliver energy deep into the brain tissue as far as 8 centimetres, helping it reach the deep areas of the brain connected with memory and with the processes of cognition accurately on target

Safe, Not Giving Rise to Heat That Is Dangerous to the Cells and the Tissue

TPS uses short pulses of sound waves of a specific kind, so it does not give rise to accumulated heat that is dangerous to the tissue, helping the treatment proceed safely and the patient feel comfortable throughout the process of the treatment

Guided Precisely with MRI Images
During the Treatment

Before the treatment, the MRI scan images of the patient will be brought into the system and aligned to correspond with the position of the head, helping the position to be identified in order to stimulate the area of the brain that is wanted more precisely

Can Be Used Together with Medicine and with Restoration by Traditional Occupational Therapy

TPS can be a part of an integrated plan of care of Alzheimer's patients, used together with treatment with medicine and with traditional restoration, in order to support the goals of the treatment of each individual patient

The Course of Treatment Uses a Short Length of Time
The Result Continues After the Treatment

TPS is usually planned as a course of 6 times within a length of time of 2 weeks, using 30 minutes each time, with treatment to maintain the result possibly every 4–6 weeks according to the symptoms and the response to the treatment

TPS Clinical Insights​

Evidence from the Clinical Trials Points to a Significantly Better Result

• It was found that the scores of assessment in the field of cognition, such as MMSE, MoCA and ADAS-Cog, became significantly better when compared with the group that received sham stimulation
• The level of the indicators in the cerebrospinal fluid connected with the degeneration of the nervous system, such as p-tau and neurofilament light chain, reduced
• The better result still continued in the period of following up, and treatment as a continuous course may help strengthen the result further
• It can be used from the early stage of dementia (MCI) up to Alzheimer's disease of the moderate stage, with most patients tolerating the treatment well, without needing to use general anaesthesia, and it is a treatment that is not surgical evidence from clinical studies (Benussi et al., 2021, 2022)

Treatment with TPS each time uses about 30-45 minutes, with no need for general anaesthesia and no need to shave the head; the patient can sit in a comfortable posture throughout the treatment

Integrated Treatment

The Intensive Programme of Restoration of the Ability of the Brain

The intensive programme of restoration of the ability of the brain | Intensive Cognitive Rehabilitation Program has the goal of restoring the important abilities that are usually affected by Alzheimer's disease, such as memory, concentration, deciding, the use of language, depending on oneself in daily life, together with giving knowledge to the carer, so that they can care for the patient suitably

The family of the patient can choose to restore with the programme of restoration of the ability of the brain on its own, or use it together with TPS | Transcranial Pulse Stimulation; if they are used alongside each other, TPS will be arranged during weeks 1–2, in order to stimulate the brain to respond to learning better, promoting the result of the programme of training

Emphasising the Restoration of the Important Abilities That Usually Decline from Alzheimer's Disease

The programme of training emphasises the restoration of the important abilities that are usually affected by Alzheimer's disease, namely memory of events (Episodic Memory), thinking, planning and deciding, the speed of processing, concentration, and the use of language

Continuous Training of 4 Hours, 3 - 5 Days a Week, Covering Every Important Dimension

The patient will receive restoration of the ability of the brain alongside aerobic exercise, training of walking and of balance, including stimulation of the brain by the physician, such as TMS, in order to support both the working of the brain and the physical ability at the same time

Cared for by Specialists Who Take Both the Patient and the Family into Account

This programme covers both the giving of knowledge and practical training for the carer, in order to help the family understand the state of the patient more, and care for and support the daily life of the patient suitably, continuing the restoration in the clinic into real life continuously

Inside the Program

The Techniques and the Technologies Used in the Restoration

Our programme combines systematic restoration of the ability of the brain, movement of the body, stimulation of the brain, and the preparing of readiness for the carer

In this, the programme of treatment that is suitable specifically to the individual will receive an assessment by the physician after the diagnosis, so that it suits the goals of the treatment and the state of the patient

Stimulating the Brain with Sound Waves of a Specific Frequency TPS | Transcranial Pulse Stimulation

An innovation of brain stimulation that is not invasive, reaching the deep part of the brain connected with memory and with the processes of cognition, used in order to promote the working of the brain; it can be used together with medicine and with occupational therapy in order to promote the result of the training

Treatment with Anti-Amyloid Beta Medicine

Treatment with a monoclonal antibody for Alzheimer's patients of the early stage, which targets the amyloid beta in the brain. The clinical evidence shows the slowing of the decline of the brain and better maintaining of the ability to live daily life

Stimulating the Brain with an Electromagnetic Wave | TMS | Transcranial Magnetic Stimulation

TMS is one of the techniques of brain stimulation that the physician may choose to use according to the suitability of each individual patient, in order to strengthen the restoration of the ability of the brain and to support both the working in the field of cognition and the physical ability

Exercise Alongside Occupational Therapy, in Order to Support the Restoration of the Brain

The care covers exercise, training of walking, balance, and physical ability, in order to promote the working of the brain and help the patient maintain mobility and be able to depend on themselves in daily life safely

Patient Results

The Results from the Restoration

Case 1 — A Slight Decline of Memory, Restoring the Symptoms with TPS on Its Own

A male patient, aged 69, who has a state of slight decline of memory (Amnestic MCI), wanted to try TPS before deciding to join the full programme. After receiving 6 sessions, the MMSE score increased by 3 points, the ability to recall words became clearly better, and the family observed that the repeating of questions reduced. At present he has decided to join the programme of a length of time of 1 month

Case 2 — Early-Stage Alzheimer's, the 1-Month Programme of Restoration of the Ability of the Brain Together with TPS

A female patient, aged 74, who has symptoms of Alzheimer's disease of the early stage, received TPS during weeks 1–2 alongside daily restoration. After completing 1 month, the MoCA score increased by 4 points, she still does the daily routine by herself using equipment to help with memory, and the burden of the carer has reduced greatly

Case 3 — Moderate-Stage Alzheimer's, Emphasising the Ability to Live Daily Life

A male patient, aged 78, who has Alzheimer's disease of the moderate stage, with the main goal of maintaining the ability to live daily life and preparing the readiness of the family to care for him suitably. After completing 1 month, the risk of falling reduced, the family can care for the daily routine with more confidence, the patient responded well to the treatment with TPS, and there is a plan to receive the next course of treatment

Medical Specialists

The Team of Specialist Physicians and the Multidisciplinary Team

Our Programs

The Programmes of Restoration

Our programmes of care of Alzheimer's patients have been designed in order to give the care that is suitable at each stage of the disease

You can consult about the symptoms and the concerns with our team, in order to receive recommendations that suit each individual patient

1-Week Program​

Brain Activation

Suitable for patients who are just beginning the care, or who need to begin with a short-term programme in order to stimulate the working of the brain

• The programme of restoration of the ability of the brain
• Integrated restoration of the nervous system and the brain can be added to the plan of restoration
• TPS can be added to the plan of restoration

From 11,400 baht

1-Month Program

Intensive Immersion

Suitable for patients who need more intensive care, with a systematic plan of restoration that corresponds with the goals of the treatment

• The advanced programme of restoration of the ability of the brain, together with TMS
• An integrated plan of restoration of the nervous system and the brain is arranged
• TPS can be added to the plan of treatment

From 110,000 baht

3-Month Program

Sustainable Cognitive Care

Suitable for those who need continuous care in the long term, in order to slow the progress of the symptoms and maintain the ability to live daily life

• The advanced programme of restoration of the ability of the brain, together with TMS
• An integrated plan of restoration of the nervous system and the brain is arranged
• Continuous restoration and care in order to promote the result in the long term

From 132,000 baht

Download Our Programme Guide

Receive the guide to the programme of care of Alzheimer's patients. Within the document there are the details of the programme, the approach of the care, the length of time, and the cost, in order to help you consider the choice that is suitable. Fill in the form in order to receive the document

Start Your Care Journey

The Steps for Receiving the Restoration

1. Consult about the Symptoms and the Goals of the Restoration with Our Team

Talk about the symptoms after a stroke, the limitations in using the body, the problems that are of concern, and the goals in the restoration, so that our team understands the overall picture and recommends the suitable approach of assessment in the first stage

2. Receive the Assessment of the Symptoms

Receive a detailed assessment by the team of physicians and the multidisciplinary team

The assessment has a cost of 6,800 baht, which can be deducted from the cost for the programme of restoration when the treatment is begun within 30 days

3. Plan the Approach of Restoration That Is Suitable

The team of physicians and the multidisciplinary team will together consider the approach of treatment that is most suitable for each individual patient, whether that is TPS on its own, the intensive programme of restoration, or care of a combined kind

4. Begin the Care According to the Plan of Treatment

The patient will begin to receive the treatment according to the plan of care designed to suit the character of the cognition, the goals in the restoration, and the stage of the disease, specifically to the individual

Frequently Asked Questions

What does the Alzheimer's programme at PYONG Rehabilitation cover

Our programme covers care of an integrated kind, from stimulating the brain with sound waves of a high frequency (TPS), the intensive restoration of the ability of the brain, exercise together with occupational therapy, through to giving knowledge and preparing the readiness of the carer, with the plan of restoration designed by the team of specialist physicians and the multidisciplinary team so that it suits the needs of each individual patient

Is it possible to receive treatment with TPS without using it together with the programme of restoration of the ability of the brain

The patient can receive treatment with TPS on its own, without it being necessary to do it together with the programme of restoration of the ability of the brain. However, in many cases we usually recommend using it together with the intensive programme of restoration, because TPS is usually arranged during weeks 1–2 in order to stimulate the brain in the first stage, so as to strengthen the result of the training for restoring the ability of the brain

What result should the patient and the family expect

Alzheimer's disease is a disease that has continuous decline. Neither TPS nor the programme of restoration can cure the disease completely, but they have the goal of helping slow the decline of the symptoms, promoting the working of the brain and the ability to live daily life, helping the patient be able to depend on themselves for longer, and helping the family have a more systematic approach of care at home

The result that can be expected may include better scores of assessment in the field of cognition, reduced psychiatric symptoms arising from the state of the brain in some patients, as well as the carer receiving knowledge and clearer practical guidance for continuous care at home

Who may be suitable for treatment with TPS

In general, those who may be suitable for treatment with TPS are patients who have a state of slight deficiency of cognition (MCI), patients who have Alzheimer's disease of the early stage, and some of the moderate stage, with the goals and the intensity of the treatment being adjusted to suit each individual patient

However, some cases may need to receive further assessment, particularly in patients who have an electronic device implanted near the skull, who have an abnormality within the skull that must still be watched, who have severe symptoms of behaviour, or who have a medical state that is not yet stable

If you are interested in receiving restoration of the symptoms of Alzheimer's disease at PYONG Rehabilitation, how should you begin

The family of the patient can begin from a consultation in the first stage with a nurse without a charge, followed by a detailed clinical assessment, with an assessment fee of 6,800 baht which can be deducted from the cost in the programme of restoration if the treatment is begun within 30 days. After that the team of specialist physicians and the multidisciplinary team will help lay out the approach of care that is most suitable for each individual patient

Questions About the Symptoms, or Wanting an Assessment of the Suitability of the Treatment

Our team is glad to give recommendations specific to the individual that are suitable for each individual patient