Getting to know Stem Cell and its role in restoration
What is the stem cell (Stem Cell)
To compare it simply, the stem cell is the "cell of origin" of our body. Normally the body has these cells to repair the parts that are worn already, but when we grow older in age or are severely injured, the number and the quality of these cells decrease. Using stem cell therapy is therefore like going in to put the problem right directly
The mechanism of the working
Many people understand wrongly that when stem cells are injected in, those cells will become new tissue immediately. But in present-day science, the main mechanism that is accepted is the "Paracrine Effect"
- It is not a transformation: stem cells do not go in and change into bone or tendon immediately, as is understood
- But it is the release of important substances: stem cells have the duty of being like a factory producing medicine, which sends out the substances Cytokines and Interleukins in order to command the surrounding cells to stop the inflammation, and stimulate the body to begin the process of repairing itself. These substances help adjust the balance of immunity, reduce pain, and slow the degeneration of diseases arising from severe inflammation excellently
Mesenchymal Stem Cell (MSC) for the knee joint and the tendons
What sources are there at present?
At present we know MSCs from 3 main sources that are well familiar:
- From one's own blood (PRP): in truth it is not a stem cell directly, but it is concentrated platelets that give a close result in respect of repair at the beginning stage
- From one's own fat or bone marrow (Autologous): it must be drawn out from the body of the patient themselves. The advantage is that it is one's own, but the disadvantage is that the quality of the cells usually ages with the age of the patient
- From the tissue of the umbilical cord (Wharton's Jelly): it is the source most popular at present, because they are the newest and freshest cells, with high effectiveness in dividing, and with high safety because there is not yet an expression through the immune system, making the body's rejection of the cells low
The medical benefits that have been accepted
- Reducing inflammation: in a degenerated knee joint or chronic inflammation of a tendon, there is inflammation at all times. MSCs go in and have the duty of reducing this state, making it possible to reduce the symptoms of pain for longer than ordinary pain-relieving medicine
- Slowing degeneration: the biological substances that the cells secrete help create a suitable state in the knee joint (Joint Environment), preventing the cartilage from being destroyed more than before
Why the high-level standard at PYONG Rehabilitation should be chosen?
At our clinic, we give importance to the "standard of safety and of the quality of the cells" as the number one matter. We therefore choose to use stem cells that have passed a process of selection at world level (the AABB standard from the United States of America), in order to be confident in 3 main respects:
- The youth of the cells (Passage 3): we choose to use cells at the stage at which they are strongest, not cells that have been cultured repeatedly, which makes the effectiveness in secreting restoring substances better than ordinary cells
- Safety at the international level: there must be registration and strict checking, both in the matter of cleanliness and of contamination, as well as checking the risk of a tumour arising, so that the patient is confident that what is injected in is the best and safest thing
- The stability of the result of the treatment: the use of cells that have a regular standard of quality helps the physician be able to predict the result of the treatment more accurately than using cells that are not of the standard
A summary for the patient: the injection of stem cells is not the waiting for a miracle for bone to grow anew, but is the use of biological technology at a high level to go in and slow the origin of the degeneration, reduce the inflammation, and open the opportunity for the body to restore itself at full effectiveness, under the highest safety